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I have three dogs, small (5lb), medium (20 lb) and large (60 lb) and all three of them love these chews. I first learned of this brand of chew at my vet's office, I had one of my dog's teeth cleaned and they suggested these (as well as the C.E.T. toothpaste) to help maintain the health and condition of my dog's teeth. I have used this product a little over two years. I each dog one chew (small for the small/medium dog and large for the large)at bedtime each night. They remind me every night when I go to bed by standing by the cabinet where the chews are stored. The only disadvantage, which is a minor thing but worth noting so you don't get surprised, the chews can leave a colored-residue on whatever bedding they are on while they chew it. My dogs like to jump up on my bed to eat them so I place a towel down for them to eat on so my duvet does not get soiled. The residue does not stain, it comes out with regular washing.
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I have ordered the C.E.T. dog chews both ways: those with the Chlorhexidine, and those without. I prefer that our dogs chew those without the Chlorhexidine for two reasons: First, the ones with Chlorhexidine have an obnoxious odor for me. But most importantly, one of my dogs has a terrible diarrhea if he has the Chlorhexidine chews. I will continue to order the C.E.T. Premium Oral Hygiene Chews WITHOUT Chlorhexidine for my pets and give the WITHOUT Chlorhexidine chews five stars!I have two Chihuahua's. One will eat anything, and the other is very picky. They both love these chews, and they keep their teeth clean.C.E.T. HEXtra Premium Oral Hygiene Chews with Chlorhexidine, Medium Dogs, 30 ChewsThese work great for reducing tartar on dogs teeth and recommended by my VET.These are for some reason, one of my dog's favorite treats, which is great because with his dental issues I always have a package in the house. They are a little expensive i think, 30 cents per treat even at this great Amazon price of $10 (at Petco even the non Hextra version is $22!) but it's a great treat because of the 10% chlorhexidine coating. I don't give them to him every day because of the high percentage of the antiseptic ingredient, even though everything i've read indicates that is not at all harmful for doggies. I give him a half of 1 every other day.
Other rawhide treats have made my dog throw up but he has never had any issues with these. Love them.
I do have 2 gripes though. 1 is that one of the ingredients is maltodextrin, it's a chemical used in sugar substitutes, which is another reason i don't give him these daily. 2ndly, I always prefer my dogs treats made in the U.S., but these ones are "A product of Mexico".
Even though my dog naturally accumulates plaque and tartar and an unbelievable fast rate, with the regimen i have in place he's doing well. I will always include these in my regimen unless something better comes along.
Keep in mind, doggy dental chews cannot replace brushing. Pet dental gels can if brushing is not an option, special water additives and even the plaqueoff powder, but these chews are great for maintenance. I also have Chlorhexidine tooth wipes for dogs, i only use them 2x a week, i brush his teeth every other day and use dental gel on days i don't brush or wipe the teeth.